New Insights into the Hendra Virus Attachment and Entry Process from Structures of the Virus G Glycoprotein and Its Complex with Ephrin-B2

Hendra virus and Nipah virus, comprising the genus Henipavirus, are recently emerged, highly pathogenic and often lethal zoonotic agents against which there are no approved therapeutics. Two surface glycoproteins, the attachment (G) and fusion (F), mediate host cell entry. The crystal structures of...

Descripción completa

Detalles Bibliográficos
Autores principales: Xu, Kai, Chan, Yee-Peng, Rajashankar, Kanagalaghatta R., Khetawat, Dimple, Yan, Lianying, Kolev, Momchil V., Broder, Christopher C., Nikolov, Dimitar B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3489827/
https://www.ncbi.nlm.nih.gov/pubmed/23144952
http://dx.doi.org/10.1371/journal.pone.0048742

Ejemplares similares

Ejemplares similares