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Sunitinib treatment does not improve blood supply but induces hypoxia in human melanoma xenografts

BACKGROUND: Antiangiogenic agents that disrupt the vascular endothelial growth factor pathway have been demonstrated to normalize tumor vasculature and improve tumor oxygenation in some studies and to induce hypoxia in others. The aim of this preclinical study was to investigate the effect of suniti...

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Detalles Bibliográficos
Autores principales:	Gaustad, Jon-Vidar, Simonsen, Trude G, Leinaas, Marit N, Rofstad, Einar K
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3489843/ https://www.ncbi.nlm.nih.gov/pubmed/22947392 http://dx.doi.org/10.1186/1471-2407-12-388

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