The Interplay of cis-Regulatory Elements Rules Circadian Rhythms in Mouse Liver

The mammalian circadian clock is driven by cell-autonomous transcriptional feedback loops that involve E-boxes, D-boxes, and ROR-elements. In peripheral organs, circadian rhythms are additionally affected by systemic factors. We show that intrinsic combinatorial gene regulation governs the liver clo...

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Detalles Bibliográficos
Autores principales: Korenčič, Anja, Bordyugov, Grigory, Košir, Rok, Rozman, Damjana, Goličnik, Marko, Herzel, Hanspeter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3489864/
https://www.ncbi.nlm.nih.gov/pubmed/23144788
http://dx.doi.org/10.1371/journal.pone.0046835

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