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The Human Homolog of Escherichia coli Endonuclease V Is a Nucleolar Protein with Affinity for Branched DNA Structures

Loss of amino groups from adenines in DNA results in the formation of hypoxanthine (Hx) bases with miscoding properties. The primary enzyme in Escherichia coli for DNA repair initiation at deaminated adenine is endonuclease V (endoV), encoded by the nfi gene, which cleaves the second phosphodiester...

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Detalles Bibliográficos
Autores principales: Fladeby, Cathrine, Vik, Erik Sebastian, Laerdahl, Jon K., Gran Neurauter, Christine, Heggelund, Julie E., Thorgaard, Eirik, Strøm-Andersen, Pernille, Bjørås, Magnar, Dalhus, Bjørn, Alseth, Ingrun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3489907/
https://www.ncbi.nlm.nih.gov/pubmed/23139746
http://dx.doi.org/10.1371/journal.pone.0047466