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The Human Homolog of Escherichia coli Endonuclease V Is a Nucleolar Protein with Affinity for Branched DNA Structures
Loss of amino groups from adenines in DNA results in the formation of hypoxanthine (Hx) bases with miscoding properties. The primary enzyme in Escherichia coli for DNA repair initiation at deaminated adenine is endonuclease V (endoV), encoded by the nfi gene, which cleaves the second phosphodiester...
Autores principales: | Fladeby, Cathrine, Vik, Erik Sebastian, Laerdahl, Jon K., Gran Neurauter, Christine, Heggelund, Julie E., Thorgaard, Eirik, Strøm-Andersen, Pernille, Bjørås, Magnar, Dalhus, Bjørn, Alseth, Ingrun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3489907/ https://www.ncbi.nlm.nih.gov/pubmed/23139746 http://dx.doi.org/10.1371/journal.pone.0047466 |
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