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Large-Scale Screen for Modifiers of Ataxin-3-Derived Polyglutamine-Induced Toxicity in Drosophila
Polyglutamine (polyQ) diseases represent a neuropathologically heterogeneous group of disorders. The common theme of these disorders is an elongated polyQ tract in otherwise unrelated proteins. So far, only symptomatic treatment can be applied to patients suffering from polyQ diseases. Despite exten...
Autores principales: | Voßfeldt, Hannes, Butzlaff, Malte, Prüßing, Katja, Ní Chárthaigh, Róisín-Ana, Karsten, Peter, Lankes, Anne, Hamm, Sabine, Simons, Mikael, Adryan, Boris, Schulz, Jörg B., Voigt, Aaron |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3489908/ https://www.ncbi.nlm.nih.gov/pubmed/23139745 http://dx.doi.org/10.1371/journal.pone.0047452 |
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