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Increased arginase II activity contributes to endothelial dysfunction through endothelial nitric oxide synthase uncoupling in aged mice

The incidence of cardiovascular disease is predicted to increase as the population ages. There is accumulating evidence that arginase upregulation is associated with impaired endothelial function. Here, we demonstrate that arginase II (ArgII) is upregulated in aortic vessels of aged mice and contrib...

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Detalles Bibliográficos
Autores principales:	Shin, Woosung, Berkowitz, Dan E., Ryoo, Sungwoo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Society for Biochemistry and Molecular Biology 2012
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3490081/ https://www.ncbi.nlm.nih.gov/pubmed/22854495 http://dx.doi.org/10.3858/emm.2012.44.10.068

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