Ghost Cell Odontogenic Carcinoma Arising from Calcifying Cystic Odontogenic Tumor: A Case Report

Ghost cell odontogenic carcinoma (GCOC) is an exceptionally rare and malignant odontogenic tumor with aggressive growth characteristics. We describe a case of GCOC which was considerably derived from a previously resected calcifying cystic odontogenic tumor (CCOT). Cellular atypia, mitotic activity,...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhu, Zhi-Yu, Chu, Zhi-Gang, Chen, Yu, Zhang, Wei-Ping, Lv, Di, Geng, Ning, Yang, Ming-Zhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Pathologists and The Korean Society for Cytopathology 2012
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3490111/
https://www.ncbi.nlm.nih.gov/pubmed/23136575
http://dx.doi.org/10.4132/KoreanJPathol.2012.46.5.478
_version_ 1782248827359592448
author Zhu, Zhi-Yu
Chu, Zhi-Gang
Chen, Yu
Zhang, Wei-Ping
Lv, Di
Geng, Ning
Yang, Ming-Zhong
author_facet Zhu, Zhi-Yu
Chu, Zhi-Gang
Chen, Yu
Zhang, Wei-Ping
Lv, Di
Geng, Ning
Yang, Ming-Zhong
author_sort Zhu, Zhi-Yu
collection PubMed
description Ghost cell odontogenic carcinoma (GCOC) is an exceptionally rare and malignant odontogenic tumor with aggressive growth characteristics. We describe a case of GCOC which was considerably derived from a previously resected calcifying cystic odontogenic tumor (CCOT). Cellular atypia, mitotic activity, Ki-67 labeling index and matrix metalloprotease-9 positive expression rate were all increased in the currently resected specimen compared to the initial one. This is a rare case of malignant transformation of CCOT to GCOC with respect to its histopathological and immunohistochemical findings.
format Online
Article
Text
id pubmed-3490111
institution National Center for Biotechnology Information
language English
publishDate 2012
publisher The Korean Society of Pathologists and The Korean Society for Cytopathology
record_format MEDLINE/PubMed
spelling pubmed-34901112012-11-07 Ghost Cell Odontogenic Carcinoma Arising from Calcifying Cystic Odontogenic Tumor: A Case Report Zhu, Zhi-Yu Chu, Zhi-Gang Chen, Yu Zhang, Wei-Ping Lv, Di Geng, Ning Yang, Ming-Zhong Korean J Pathol Case Report Ghost cell odontogenic carcinoma (GCOC) is an exceptionally rare and malignant odontogenic tumor with aggressive growth characteristics. We describe a case of GCOC which was considerably derived from a previously resected calcifying cystic odontogenic tumor (CCOT). Cellular atypia, mitotic activity, Ki-67 labeling index and matrix metalloprotease-9 positive expression rate were all increased in the currently resected specimen compared to the initial one. This is a rare case of malignant transformation of CCOT to GCOC with respect to its histopathological and immunohistochemical findings. The Korean Society of Pathologists and The Korean Society for Cytopathology 2012-10 2012-10-25 /pmc/articles/PMC3490111/ /pubmed/23136575 http://dx.doi.org/10.4132/KoreanJPathol.2012.46.5.478 Text en © 2012 The Korean Society of Pathologists/The Korean Society for Cytopathology http://creativecommons.org/licenses/by-nc/3.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Zhu, Zhi-Yu
Chu, Zhi-Gang
Chen, Yu
Zhang, Wei-Ping
Lv, Di
Geng, Ning
Yang, Ming-Zhong
Ghost Cell Odontogenic Carcinoma Arising from Calcifying Cystic Odontogenic Tumor: A Case Report
title Ghost Cell Odontogenic Carcinoma Arising from Calcifying Cystic Odontogenic Tumor: A Case Report
title_full Ghost Cell Odontogenic Carcinoma Arising from Calcifying Cystic Odontogenic Tumor: A Case Report
title_fullStr Ghost Cell Odontogenic Carcinoma Arising from Calcifying Cystic Odontogenic Tumor: A Case Report
title_full_unstemmed Ghost Cell Odontogenic Carcinoma Arising from Calcifying Cystic Odontogenic Tumor: A Case Report
title_short Ghost Cell Odontogenic Carcinoma Arising from Calcifying Cystic Odontogenic Tumor: A Case Report
title_sort ghost cell odontogenic carcinoma arising from calcifying cystic odontogenic tumor: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3490111/
https://www.ncbi.nlm.nih.gov/pubmed/23136575
http://dx.doi.org/10.4132/KoreanJPathol.2012.46.5.478
work_keys_str_mv AT zhuzhiyu ghostcellodontogeniccarcinomaarisingfromcalcifyingcysticodontogenictumoracasereport
AT chuzhigang ghostcellodontogeniccarcinomaarisingfromcalcifyingcysticodontogenictumoracasereport
AT chenyu ghostcellodontogeniccarcinomaarisingfromcalcifyingcysticodontogenictumoracasereport
AT zhangweiping ghostcellodontogeniccarcinomaarisingfromcalcifyingcysticodontogenictumoracasereport
AT lvdi ghostcellodontogeniccarcinomaarisingfromcalcifyingcysticodontogenictumoracasereport
AT gengning ghostcellodontogeniccarcinomaarisingfromcalcifyingcysticodontogenictumoracasereport
AT yangmingzhong ghostcellodontogeniccarcinomaarisingfromcalcifyingcysticodontogenictumoracasereport

Ejemplares similares