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Strain conformation, primary structure and the propagation of the yeast prion [PSI(+)]
Prion proteins can adopt multiple different infectious strain conformations. Here we examine how the sequence of a prion protein affects its capacity to propagate specific conformations by exploiting our ability to create two distinct infectious conformations of the yeast [PSI(+)] prion protein Sup3...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3490428/ https://www.ncbi.nlm.nih.gov/pubmed/21423194 http://dx.doi.org/10.1038/nsmb.2030 |