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Likelihood based observability analysis and confidence intervals for predictions of dynamic models

BACKGROUND: Predicting a system’s behavior based on a mathematical model is a primary task in Systems Biology. If the model parameters are estimated from experimental data, the parameter uncertainty has to be translated into confidence intervals for model predictions. For dynamic models of biochemic...

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Detalles Bibliográficos
Autores principales:	Kreutz, Clemens, Raue, Andreas, Timmer, Jens
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Methodology Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3490710/ https://www.ncbi.nlm.nih.gov/pubmed/22947028 http://dx.doi.org/10.1186/1752-0509-6-120

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