Dual Suppression of the Cyclin-Dependent Kinase Inhibitors CDKN2C and CDKN1A in Human Melanoma

Resistance to BRAF(V600E) inhibitors is associated with reactivation of mitogen-activated protein kinase (MAPK) signaling at different levels in melanoma. To identify downstream effectors of MAPK signaling that could be used as potential additional therapeutic targets for BRAF(V600E) inhibitors, we...

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Detalles Bibliográficos
Autores principales: Jalili, Ahmad, Wagner, Christine, Pashenkov, Mikhail, Pathria, Gaurav, Mertz, Kirsten D., Widlund, Hans R., Lupien, Mathieu, Brunet, Jean- Philippe, Golub, Todd R., Stingl, Georg, Fisher, David E., Ramaswamy, Sridhar, Wagner, Stephan N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3490842/
https://www.ncbi.nlm.nih.gov/pubmed/22997239
http://dx.doi.org/10.1093/jnci/djs373

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