Cellulase Linkers Are Optimized Based on Domain Type and Function: Insights from Sequence Analysis, Biophysical Measurements, and Molecular Simulation

Cellulase enzymes deconstruct cellulose to glucose, and are often comprised of glycosylated linkers connecting glycoside hydrolases (GHs) to carbohydrate-binding modules (CBMs). Although linker modifications can alter cellulase activity, the functional role of linkers beyond domain connectivity rema...

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Detalles Bibliográficos
Autores principales: Sammond, Deanne W., Payne, Christina M., Brunecky, Roman, Himmel, Michael E., Crowley, Michael F., Beckham, Gregg T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3490864/
https://www.ncbi.nlm.nih.gov/pubmed/23139804
http://dx.doi.org/10.1371/journal.pone.0048615

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3490864/
https://www.ncbi.nlm.nih.gov/pubmed/23139804
http://dx.doi.org/10.1371/journal.pone.0048615

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