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Towards Optimising the Production of and Expression from Polycistronic Vectors in Embryonic Stem Cells

Polycistronic vectors linked by self-processing 2A peptides have been successfully used in cellular reprogramming. The expression of these vectors has yet to be well documented in embryonic stem cells. In the present study, we generated expression cassettes containing combinatorial arrangements of 3...

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Detalles Bibliográficos
Autores principales: Gao, Steven Y., Jack, Michelle M., O’Neill, Christopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3490874/
https://www.ncbi.nlm.nih.gov/pubmed/23139810
http://dx.doi.org/10.1371/journal.pone.0048668