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Reduction of Type IV Collagen by Upregulated miR-29 in Normal Elderly Mouse and klotho-Deficient, Senescence-Model Mouse

MicroRNA (miRNA), a small non-coding RNA that functions as a mediator in gene silencing, plays important roles in gene regulation in various vital functions and activities. Here we show that the miR-29 members are upregulated in klotho-deficient [klotho(−/−)] mice, a senescence-model animal, and als...

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Detalles Bibliográficos
Autores principales:	Takahashi, Masaki, Eda, Akiko, Fukushima, Tatsunobu, Hohjoh, Hirohiko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3490916/ https://www.ncbi.nlm.nih.gov/pubmed/23139829 http://dx.doi.org/10.1371/journal.pone.0048974

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