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Apolipoprotein C-I is an APOE genotype-dependent suppressor of glial activation
BACKGROUND: Inheritance of the human ϵ4 allele of the apolipoprotein (apo) E gene (APOE) significantly increases the risk of developing Alzheimer’s disease (AD), in addition to adversely influencing clinical outcomes of other neurologic diseases. While apoE isoforms differentially interact with amyl...
Autores principales: | Cudaback, Eiron, Li, Xianwu, Yang, Yue, Yoo, Thomas, Montine, Kathleen S, Craft, Suzanne, Montine, Thomas J, Keene, Christopher Dirk |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3490924/ https://www.ncbi.nlm.nih.gov/pubmed/22883744 http://dx.doi.org/10.1186/1742-2094-9-192 |
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