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Medullary thyroid cancer in a 9-week-old infant with familial MEN 2B: Implications for timing of prophylactic thyroidectomy
BACKGROUND: Patients with Multiple Endocrine Neoplasia type 2 (MEN 2) are at high risk of developing aggressive medullary thyroid carcinoma (MTC) in childhood, with the highest risk in those with MEN type 2B (of whom >95% have an M918T RET proto-oncogene mutation). Metastatic MTC has been reporte...
Autores principales: | Shankar, Roopa Kanakatti, Rutter, Michael J, Chernausek, Steven D, Samuels, Paul J, Mo, Jun Qin, Rutter, Meilan M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3490942/ https://www.ncbi.nlm.nih.gov/pubmed/22992277 http://dx.doi.org/10.1186/1687-9856-2012-25 |
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