Folliculin, the Product of the Birt-Hogg-Dube Tumor Suppressor Gene, Interacts with the Adherens Junction Protein p0071 to Regulate Cell-Cell Adhesion

Birt-Hogg-Dube (BHD) is a tumor suppressor gene syndrome associated with fibrofolliculomas, cystic lung disease, and chromophobe renal cell carcinoma. In seeking to elucidate the pathogenesis of BHD, we discovered a physical interaction between folliculin (FLCN), the protein product of the BHD gene,...

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Detalles Bibliográficos
Autores principales: Medvetz, Doug A., Khabibullin, Damir, Hariharan, Venkatesh, Ongusaha, Pat P., Goncharova, Elena A., Schlechter, Tanja, Darling, Thomas N., Hofmann, Ilse, Krymskaya, Vera P., Liao, James K., Huang, Hayden, Henske, Elizabeth P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3490959/
https://www.ncbi.nlm.nih.gov/pubmed/23139756
http://dx.doi.org/10.1371/journal.pone.0047842

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