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PAK signaling in cancer

Transformation of a normal cell to a cancer cell is caused by mutations in genes that regulate proliferation, apoptosis, and invasion. Small GTPases such as Ras, Rho, Rac and Cdc42 orchestrate many of the signals that are required for malignant transformation. The p21-activated kinases (PAKs) are ef...

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Detalles Bibliográficos
Autores principales: Ye, Diana Zi, Field, Jeffrey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3490961/
https://www.ncbi.nlm.nih.gov/pubmed/23162742
http://dx.doi.org/10.4161/cl.21882

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