Decreased Expression of Synapse-Related Genes and Loss of Synapses in Major Depressive Disorder

Previous imaging and postmortem studies have reported a reduction in brain volume and a decrease in the size and density of neurons in the dorsolateral prefrontal cortex (dlPFC, area 9) of subjects with major depressive disorder (MDD).(1,2) These findings suggest that synapse number and function are...

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Detalles Bibliográficos
Autores principales: Kang, H.J., Voleti, B., Hajszan, T., Rajkowska, G., Stockmeier, C., Licznerski, P., Lepack, A., Majik, M.S., Jeong, L.S., Banasr, M., Son, H., Duman, R.S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3491115/
https://www.ncbi.nlm.nih.gov/pubmed/22885997
http://dx.doi.org/10.1038/nm.2886

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