TGFβ1 Overexpression by Keratinocytes Alters Skin Dendritic Cell Homeostasis and Enhances Contact Hypersensitivity

Overexpression of Transforming Growth Factor Beta1 (TGFβ1) in mouse epidermis causes cutaneous inflammation and keratinocyte hyperproliferation. Here, we examined acute effects of TGFβ1 overproduction by keratinocytes on skin dendritic cells (DCs). TGFβ1 induction for 2 and 4 days increased numbers...

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Detalles Bibliográficos
Autores principales: Mohammed, Javed, Gunderson, Andrew, Khong, Hong-Hanh, Koubek, Richard, Udey, Mark C., Glick, Adam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3491121/
https://www.ncbi.nlm.nih.gov/pubmed/22832490
http://dx.doi.org/10.1038/jid.2012.241

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3491121/
https://www.ncbi.nlm.nih.gov/pubmed/22832490
http://dx.doi.org/10.1038/jid.2012.241

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