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In vivo Genome Editing Using High Efficiency TALENs

The zebrafish (Danio rerio) is increasingly being used to study basic vertebrate biology and human disease using a rich array of in vivo genetic and molecular tools. However, the inability to readily modify the genome in a targeted fashion has been a bottleneck in the field. Here we show that improv...

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Detalles Bibliográficos
Autores principales:	Bedell, Victoria M., Wang, Ying, Campbell, Jarryd M., Poshusta, Tanya L., Starker, Colby G., Krug, Randall G., Tan, Wenfang, Penheiter, Sumedha G., Ma, Alvin C., Leung, Anskar Y.H., Fahrenkrug, Scott C., Carlson, Daniel F., Voytas, Daniel F., Clark, Karl J., Essner, Jeffrey J., Ekker, Stephen C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2012
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3491146/ https://www.ncbi.nlm.nih.gov/pubmed/23000899 http://dx.doi.org/10.1038/nature11537

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