Cargando…
E2F mediates enhanced alternative polyadenylation in proliferation
BACKGROUND: The majority of mammalian genes contain multiple poly(A) sites in their 3' UTRs. Alternative cleavage and polyadenylation are emerging as an important layer of gene regulation as they generate transcript isoforms that differ in their 3' UTRs, thereby modulating genes' resp...
Autores principales: | Elkon, Ran, Drost, Jarno, van Haaften, Gijs, Jenal, Mathias, Schrier, Mariette, Oude Vrielink, Joachim AF, Agami, Reuven |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3491381/ https://www.ncbi.nlm.nih.gov/pubmed/22747694 http://dx.doi.org/10.1186/gb-2012-13-7-r59 |
Ejemplares similares
-
p53 induces transcriptional and translational programs to suppress cell proliferation and growth
por: Loayza-Puch, Fabricio, et al.
Publicado: (2013) -
Transcription Impacts the Efficiency of mRNA Translation via Co-transcriptional N6-adenosine Methylation
por: Slobodin, Boris, et al.
Publicado: (2017) -
Alternative cleavage and polyadenylation generates downstream uncapped RNA isoforms with translation potential
por: Malka, Yuval, et al.
Publicado: (2022) -
Removal of AU Bias from Microarray mRNA Expression Data Enhances Computational Identification of Active MicroRNAs
por: Elkon, Ran, et al.
Publicado: (2008) -
3′UTR-Mediated Gene Silencing of the Mixed Lineage Leukemia (MLL) Gene
por: Gomez-Benito, Maria, et al.
Publicado: (2011)