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CIDeR: multifactorial interaction networks in human diseases

The pathobiology of common diseases is influenced by heterogeneous factors interacting in complex networks. CIDeR http://mips.helmholtz-muenchen.de/cider/ is a publicly available, manually curated, integrative database of metabolic and neurological disorders. The resource provides structured informa...

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Detalles Bibliográficos
Autores principales: Lechner, Martin, Höhn, Veit, Brauner, Barbara, Dunger, Irmtraud, Fobo, Gisela, Frishman, Goar, Montrone, Corinna, Kastenmüller, Gabi, Waegele, Brigitte, Ruepp, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3491383/
https://www.ncbi.nlm.nih.gov/pubmed/22809392
http://dx.doi.org/10.1186/gb-2012-13-7-r62
Descripción
Sumario:The pathobiology of common diseases is influenced by heterogeneous factors interacting in complex networks. CIDeR http://mips.helmholtz-muenchen.de/cider/ is a publicly available, manually curated, integrative database of metabolic and neurological disorders. The resource provides structured information on 18,813 experimentally validated interactions between molecules, bioprocesses and environmental factors extracted from the scientific literature. Systematic annotation and interactive graphical representation of disease networks make CIDeR a versatile knowledge base for biologists, analysis of large-scale data and systems biology approaches.