Cargando…

Functional analysis of transcription factor binding sites in human promoters

BACKGROUND: The binding of transcription factors to specific locations in the genome is integral to the orchestration of transcriptional regulation in cells. To characterize transcription factor binding site function on a large scale, we predicted and mutagenized 455 binding sites in human promoters...

Descripción completa

Detalles Bibliográficos
Autores principales:	Whitfield, Troy W, Wang, Jie, Collins, Patrick J, Partridge, E Christopher, Aldred, Shelley Force, Trinklein, Nathan D, Myers, Richard M, Weng, Zhiping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3491394/ https://www.ncbi.nlm.nih.gov/pubmed/22951020 http://dx.doi.org/10.1186/gb-2012-13-9-r50

Ejemplares similares

The ets-Related Transcription Factor GABP Directs Bidirectional Transcription
por: Collins, Patrick J, et al.
Publicado: (2007)

A functional analysis of the CREB signaling pathway using HaloCHIP-chip and high throughput reporter assays
por: Hartzell, Danette D, et al.
Publicado: (2009)

Promoter-distal RNA polymerase II binding discriminates active from inactive CCAAT/ enhancer-binding protein beta binding sites
por: Savic, Daniel, et al.
Publicado: (2015)

Mapping genome-wide transcription factor binding sites in frozen tissues
por: Savic, Daniel, et al.
Publicado: (2013)

Functional Profiling Reveals Critical Role for miRNA in Differentiation of Human Mesenchymal Stem Cells
por: Schoolmeesters, Angela, et al.
Publicado: (2009)

Genome-Wide Identification of Transcription Start Sites, Promoters and Transcription Factor Binding Sites in E. coli
por: Mendoza-Vargas, Alfredo, et al.
Publicado: (2009)

Genome-Wide Discovery of Drug-Dependent Human Liver Regulatory Elements
por: Smith, Robin P., et al.
Publicado: (2014)

Sequence features and chromatin structure around the genomic regions bound by 119 human transcription factors
por: Wang, Jie, et al.
Publicado: (2012)

Genomic Binding Profiles of Functionally Distinct RNA Polymerase III Transcription Complexes in Human Cells
por: Moqtaderi, Zarmik, et al.
Publicado: (2010)

The Insulator Binding Protein CTCF Positions 20 Nucleosomes around Its Binding Sites across the Human Genome
por: Fu, Yutao, et al.
Publicado: (2008)

Identifying Functional Transcription Factor Binding Sites in Yeast by Considering Their Positional Preference in the Promoters
por: Lai, Fu-Jou, et al.
Publicado: (2013)

Efficient tumor killing and minimal cytokine release with novel T-cell agonist bispecific antibodies
por: Trinklein, Nathan D., et al.
Publicado: (2019)

Identification of functional modules that correlate with phenotypic difference: the influence of network topology
por: Hung, Jui-Hung, et al.
Publicado: (2010)

Kaiso Directs the Transcriptional Corepressor MTG16 to the Kaiso Binding Site in Target Promoters
por: Barrett, Caitlyn W., et al.
Publicado: (2012)

Genome-Wide Analysis of Transcription Factor Binding Sites Based on ChIP-Seq Data
por: Valouev, Anton, et al.
Publicado: (2008)

Prediction of transcription factor bindings sites affected by SNPs located at the osteopontin promoter
por: Briones-Orta, Marco Antonio, et al.
Publicado: (2017)

Scoring functions for transcription factor binding site prediction
por: Friberg, Markus, et al.
Publicado: (2005)

Pseudocounts for transcription factor binding sites
por: Nishida, Keishin, et al.
Publicado: (2009)

Perspective: Designing T-Cell Engagers With Better Therapeutic Windows
por: Vafa, Omid, et al.
Publicado: (2020)

Genome-wide transcription factor binding site/promoter databases for the analysis of gene sets and co-occurrence of transcription factor binding motifs
por: Veerla, Srinivas, et al.
Publicado: (2010)

Transcription Factor Binding Site Positioning in Yeast: Proximal Promoter Motifs Characterize TATA-Less Promoters
por: Erb, Ionas, et al.
Publicado: (2011)

Identification of virion-associated transcriptional transactivator (VATT) of SGIV ICP46 promoter and their binding site on promoter
por: Xia, Li-Qun, et al.
Publicado: (2019)

The orientation of transcription factor binding site motifs in gene promoter regions: does it matter?
por: Lis, Monika, et al.
Publicado: (2016)

Backup transcription factor binding sites protect human genes from mutations in the promoter
por: Brown, Jay C.
Publicado: (2023)

Frequent Gain and Loss of Functional Transcription Factor Binding Sites
por: Doniger, Scott W, et al.
Publicado: (2007)

Genome-Wide Profiling of H3K56 Acetylation and Transcription Factor Binding Sites in Human Adipocytes
por: Lo, Kinyui Alice, et al.
Publicado: (2011)

Adaptive evolution of transcription factor binding sites
por: Berg, Johannes, et al.
Publicado: (2004)

Mutations and Binding Sites of Human Transcription Factors
por: Kamanu, Frederick Kinyua, et al.
Publicado: (2012)

Dynamics of Transcription Factor Binding Site Evolution
por: Tuğrul, Murat, et al.
Publicado: (2015)

Characterization of Binding Sites of Eukaryotic Transcription Factors
por: Qian, Jiang, et al.
Publicado: (2006)

Disentangling transcription factor binding site complexity
por: Eggeling, Ralf
Publicado: (2018)

Genetic Variation in Transcription Factor Binding Sites
por: Santpere, Gabriel
Publicado: (2023)

ncDNA and drift drive binding site accumulation
por: Ruths, Troy, et al.
Publicado: (2012)

A novel SATB1 binding site in the BCL2 promoter region possesses transcriptional regulatory function()
por: Gong, Feiran, et al.
Publicado: (2010)

Identification of Functional Transcriptional Binding Sites within Chicken Abcg2 Gene Promoter and Screening Its Regulators
por: Zhang, Yujuan, et al.
Publicado: (2020)

Programmable gene regulation for metabolic engineering using decoy transcription factor binding sites
por: Wang, Tiebin, et al.
Publicado: (2020)

Evolution and Selection in Yeast Promoters: Analyzing the Combined Effect of Diverse Transcription Factor Binding Sites
por: Raijman, Daniela, et al.
Publicado: (2008)

Discovery of SMAD4 promoters, transcription factor binding sites and deletions in juvenile polyposis patients
por: Calva, Daniel, et al.
Publicado: (2011)

Erratum to: ‘The orientation of transcription factor binding site motifs in gene promoter regions: does it matter?’
por: Lis, Monika, et al.
Publicado: (2016)

Unraveling determinants of transcription factor binding outside the core binding site
por: Levo, Michal, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_aighlgcjgv5b9tgn8kd04dhpk0