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BatMeth: improved mapper for bisulfite sequencing reads on DNA methylation

DNA methylation plays a crucial role in higher organisms. Coupling bisulfite treatment with next generation sequencing enables the interrogation of 5-methylcytosine sites in the genome. However, bisulfite conversion introduces mismatches between the reads and the reference genome, which makes mappin...

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Detalles Bibliográficos
Autores principales:	Lim, Jing-Quan, Tennakoon, Chandana, Li, Guoliang, Wong, Eleanor, Ruan, Yijun, Wei, Chia-Lin, Sung, Wing-Kin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Method
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3491410/ https://www.ncbi.nlm.nih.gov/pubmed/23034162 http://dx.doi.org/10.1186/gb-2012-13-10-r82

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