Genetic partitioning of interleukin-6 signalling in mice dissociates Stat3 from Smad3-mediated lung fibrosis

Idiopathic pulmonary fibrosis (IPF) is a fatal disease that is unresponsive to current therapies and characterized by excessive collagen deposition and subsequent fibrosis. While inflammatory cytokines, including interleukin (IL)-6, are elevated in IPF, the molecular mechanisms that underlie this di...

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Detalles Bibliográficos
Autores principales: O'Donoghue, Robert J J, Knight, Darryl A, Richards, Carl D, Prêle, Cecilia M, Lau, Hui Ling, Jarnicki, Andrew G, Jones, Jessica, Bozinovski, Steven, Vlahos, Ross, Thiem, Stefan, McKenzie, Brent S, Wang, Bo, Stumbles, Philip, Laurent, Geoffrey J, McAnulty, Robin J, Rose-John, Stefan, Zhu, Hong Jian, Anderson, Gary P, Ernst, Matthias R, Mutsaers, Steven E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2012
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3491826/
https://www.ncbi.nlm.nih.gov/pubmed/22684844
http://dx.doi.org/10.1002/emmm.201100604

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