A mouse model for distal renal tubular acidosis reveals a previously unrecognized role of the V-ATPase a4 subunit in the proximal tubule

The V-ATPase is a multisubunit complex that transports protons across membranes. Mutations of its B1 or a4 subunit are associated with distal renal tubular acidosis and deafness. In the kidney, the a4 subunit is expressed in intercalated cells of the distal nephron, where the V-ATPase controls acid/...

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Detalles Bibliográficos
Autores principales: Hennings, J Christopher, Picard, Nicolas, Huebner, Antje K, Stauber, Tobias, Maier, Hannes, Brown, Dennis, Jentsch, Thomas J, Vargas-Poussou, Rosa, Eladari, Dominique, Hübner, Christian A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2012
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3491836/
https://www.ncbi.nlm.nih.gov/pubmed/22933323
http://dx.doi.org/10.1002/emmm.201201527

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3491836/
https://www.ncbi.nlm.nih.gov/pubmed/22933323
http://dx.doi.org/10.1002/emmm.201201527

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