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Huntington's Disease and its therapeutic target genes: a global functional profile based on the HD Research Crossroads database
BACKGROUND: Huntington’s disease (HD) is a fatal progressive neurodegenerative disorder caused by the expansion of the polyglutamine repeat region in the huntingtin gene. Although the disease is triggered by the mutation of a single gene, intensive research has linked numerous other genes to its pat...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3492045/ https://www.ncbi.nlm.nih.gov/pubmed/22741533 http://dx.doi.org/10.1186/1471-2377-12-47 |