Cargando…

The effects of levosimendan on brain metabolism during initial recovery from global transient ischaemia/hypoxia

BACKROUND: Neuroprotective strategies after cardiopulmonary resuscitation are currently the focus of experimental and clinical research. Levosimendan has been proposed as a promising drug candidate because of its cardioprotective properties, improved haemodynamic effects in vivo and reduced traumati...

Descripción completa

Detalles Bibliográficos
Autores principales:	Roehl, Anna B, Zoremba, Norbert, Kipp, Markus, Schiefer, Johannes, Goetzenich, Andreas, Bleilevens, Christian, Kuehn-Velten, Nikolaus, Tolba, Rene, Rossaint, Rolf, Hein, Marc
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3492141/ https://www.ncbi.nlm.nih.gov/pubmed/22920500 http://dx.doi.org/10.1186/1471-2377-12-81

Ejemplares similares

Levosimendan limits reperfusion injury in a rat middle cerebral artery occlusion (MCAO) model
por: Hein, Marc, et al.
Publicado: (2013)

Neuroprotective properties of levosimendan in an in vitro model of traumatic brain injury
por: Roehl, Anna B, et al.
Publicado: (2010)

Interstitial lactate, lactate/pyruvate and glucose in rat muscle before, during and in the recovery from global hypoxia
por: Zoremba, Norbert, et al.
Publicado: (2014)

Recovery of Diaphragm Function following Mechanical Ventilation in a Rodent Model
por: Bruells, Christian S., et al.
Publicado: (2014)

Accuracy of the Masimo Pronto-7(®) system in patients with left ventricular assist device
por: Bruells, Christian S, et al.
Publicado: (2013)

Heating capabilities of small fluid warming systems
por: Zoremba, Norbert, et al.
Publicado: (2018)

Cold Preflush of Porcine Kidney Grafts Prior to Normothermic Machine Perfusion Aggravates Ischemia Reperfusion Injury
por: Fabry, Gregor, et al.
Publicado: (2019)

Argon Induces Protective Effects in Cardiomyocytes during the Second Window of Preconditioning
por: Mayer, Britta, et al.
Publicado: (2016)

Adaptation to acute pulmonary hypertension in pigs
por: Mechelinck, Mare, et al.
Publicado: (2018)

Editorial: Neuroinflammation in hypoxia and ischaemia
por: Jenkins, Stuart, et al.
Publicado: (2022)

Short-term elevation of intracranial pressure does neither influence duodenal motility nor frequency of bolus transport events: a porcine model
por: Schnoor, Joerg, et al.
Publicado: (2006)

Update of the organoprotective properties of xenon and argon: from bench to beside
por: Anna, Roehl, et al.
Publicado: (2020)

The use of the Airtraq(® )optical laryngoscope for routine tracheal intubation in high-risk cardio-surgical patients
por: Schälte, Gereon, et al.
Publicado: (2011)

Layperson mouth-to-mask ventilation using a modified I-gel laryngeal mask after brief onsite instruction: a manikin-based feasibility trial
por: Schälte, Gereon, et al.
Publicado: (2016)

Acceleration sensors in abdominal wall position as a non-invasive approach to detect early breathing alterations induced by intolerance of increased airway resistance
por: Breuer, Thomas, et al.
Publicado: (2017)

Laypersons can successfully place supraglottic airways with 3 minutes of training. A comparison of four different devices in the manikin
por: Schälte, Gereon, et al.
Publicado: (2011)

Taurine as Antioxidant in a Novel Cell- and Oxygen Carrier-Free Perfusate for Normothermic Machine Perfusion of Porcine Kidneys
por: Zarnitz, Laura, et al.
Publicado: (2023)

Levosimendan Relaxes Pulmonary Arteries and Veins in Precision-Cut Lung Slices - The Role of K(ATP)-Channels, cAMP and cGMP
por: Rieg, Annette D., et al.
Publicado: (2013)

The Role of Macrophage Migration Inhibitory Factor in Anesthetic-Induced Myocardial Preconditioning
por: Goetzenich, Andreas, et al.
Publicado: (2014)

Does a 4 diagram manual enable laypersons to operate the laryngeal mask supreme(®)? A pilot study in the manikin
por: Schälte, Gereon, et al.
Publicado: (2012)

Neonatal Hypoxia Ischaemia: Mechanisms, Models, and Therapeutic Challenges
por: Millar, Lancelot J., et al.
Publicado: (2017)

Influence of Vitamin C on Antioxidant Capacity of In Vitro Perfused Porcine Kidneys
por: Bleilevens, Christian, et al.
Publicado: (2019)

HBOC-301 in Porcine Kidney Normothermic Machine Perfusion and the Effect of Vitamin C on Methemoglobin Formation
por: Edgworth, Eileen, et al.
Publicado: (2022)

The effects of levosimendan and glibenclamide on circulatory and metabolic variables in a canine model of acute hypoxia
por: Schwarte, Lothar A., et al.
Publicado: (2011)

Milrinone is preferred to levosimendan for mesenteric perfusion in hypoxia-reoxygenated newborn piglets treated with dopamine
por: Manouchehri, Namdar, et al.
Publicado: (2012)

Systemic inflammation affects reperfusion following transient cerebral ischaemia
por: Burrows, F., et al.
Publicado: (2016)

Platelet count reduction during in vitro membrane oxygenation affects platelet activation, neutrophil extracellular trap formation and clot stability, but does not prevent clotting
por: Winnersbach, Patrick, et al.
Publicado: (2021)

Alpha-adrenergic receptor activation after fetal hypoxia-ischaemia suppresses transient epileptiform activity and limits loss of oligodendrocytes and hippocampal neurons
por: Dhillon, Simerdeep K, et al.
Publicado: (2023)

Efficacy of levosimendan in shock
por: McLean, A, et al.
Publicado: (2004)

Levosimendan in cardiac surgery
por: Harjola, V, et al.
Publicado: (2004)

Effects of different fibrinogen concentrations on blood loss and coagulation parameters in a pig model of coagulopathy with blunt liver injury
por: Grottke, Oliver, et al.
Publicado: (2010)

Oxygen inhalation improves postoperative survival in ketamine-xylazine anaesthetised rats: An observational study
por: Mechelinck, Mare, et al.
Publicado: (2019)

Haemodynamic Instability and Brain Injury in Neonates Exposed to Hypoxia–Ischaemia
por: Badurdeen, Shiraz, et al.
Publicado: (2019)

Efficacy of melatonin in term neonatal models of perinatal hypoxia‐ischaemia
por: Pang, Raymand, et al.
Publicado: (2022)

Effects of iNOS in Hepatic Warm Ischaemia and Reperfusion Models in Mice and Rats: A Systematic Review and Meta-Analysis
por: Nakatake, Richi, et al.
Publicado: (2022)

Solulin reduces infarct volume and regulates gene-expression in transient middle cerebral artery occlusion in rats
por: Ryang, Yu-Mi, et al.
Publicado: (2011)

Microfluidic cell sorting: Towards improved biocompatibility of extracorporeal lung assist devices
por: Bleilevens, Christian, et al.
Publicado: (2018)

Effects of hypoxia versus ischaemia on vascular functions of isolated rat thoracic aorta: revisiting the in vitro vascular ischaemia/reperfusion model
por: Orhan, Halit Güner, et al.
Publicado: (2023)

Impact of neonatal hypoxia‐ischaemia on oligodendrocyte survival, maturation and myelinating potential
por: Ziemka‐Nalecz, Malgorzata, et al.
Publicado: (2017)

Levosimendan: experience of an adult ICU
por: Lippett, S, et al.
Publicado: (2006)

Cannot write session to /tmp/vufind_sessions/sess_s7qv3fdn8m7m0o4tuhm5f6lbvr