Cargando…
NDV-induced apoptosis in absence of Bax; evidence of involvement of apoptotic proteins upstream of mitochondria
BACKGROUND: Recently it was shown that following infection of HeLa cells with Newcastle disease virus (NDV), the matrix (M) protein binds to Bax and subsequently the intrinsic pathway of apoptosis is activated. Moreover, there was very little alteration on mRNA and protein levels of Bax and Bcl-2 af...
Autores principales: | Molouki, Aidin, Yusoff, Khatijah |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3492152/ https://www.ncbi.nlm.nih.gov/pubmed/22935147 http://dx.doi.org/10.1186/1743-422X-9-179 |
Ejemplares similares
-
Rapid Generation of a Recombinant Genotype VIII Newcastle Disease Virus (NDV) Using Full-Length Synthetic cDNA
por: Murulitharan, Kavitha, et al.
Publicado: (2021) -
The matrix (M) protein of newcastle disease virus binds to human bax through its BH3 domain
por: Molouki, Aidin, et al.
Publicado: (2011) -
Bax Function in the Absence of Mitochondria in the Primitive Protozoan Giardia lamblia
por: Hehl, Adrian B., et al.
Publicado: (2007) -
Inhibition of apoptotic Bax translocation to the mitochondria is a central function of parkin
por: Charan, R A, et al.
Publicado: (2014) -
Movement of Bax from the Cytosol to Mitochondria during Apoptosis
por: Wolter, Keith G., et al.
Publicado: (1997)