Aging induced decline in T-lymphopoiesis is primarily dependent on status of progenitor niches in the bone marrow and thymus

Age-related decline in the generation of T cells is associated with two primary lymphoid organs, the bone marrow (BM) and thymus. Both organs contain lympho-hematopoietic progenitor/stem cells (LPCs) and non-hematopoietic stromal/niche cells. Murine model showed this decline is not due to reduced qu...

Descripción completa

Detalles Bibliográficos
Autores principales: Sun, Liguang, Brown, Robert, Chen, Shande, Zhuge, Qichuan, Su, Dong-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2012
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3492225/
https://www.ncbi.nlm.nih.gov/pubmed/23047952

Ejemplares similares

Ejemplares similares