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RhTFAM treatment stimulates mitochondrial oxidative metabolism and improves memory in aged mice

Mitochondrial function declines with age in postmitotic tissues such as brain, heart and skeletal muscle. Despite weekly exercise, aged mice showed substantial losses of mtDNA gene copy numbers and reductions in mtDNA gene transcription and mitobiogenesis signaling in brain and heart. We treated the...

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Detalles Bibliográficos
Autores principales:	Thomas, Ravindar R., Khan, Shaharyar M., Smigrodzki, Rafal M., Onyango, Isaac G., Dennis, Jameel, Khan, Omer M., Portell, Francisco R., Bennett, James P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2012
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3492226/ https://www.ncbi.nlm.nih.gov/pubmed/23075607

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