Cargando…
Use of the Comet-FISH Assay to Compare DNA Damage and Repair in p53 and hTERT Genes following Ionizing Radiation
The alkaline single cell gel electrophoresis (comet) assay can be combined with fluorescent in situ hybridisation (FISH) methodology in order to investigate the localisation of specific gene domains within an individual cell. The number and position of the fluorescent signal(s) provides information...
Autores principales: | McKenna, Declan J., Doherty, Bernadette A., Downes, C. Stephen, McKeown, Stephanie R., McKelvey-Martin, Valerie J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3492288/ https://www.ncbi.nlm.nih.gov/pubmed/23145163 http://dx.doi.org/10.1371/journal.pone.0049364 |
Ejemplares similares
-
Potential use of the alkaline comet assay as a predictor of bladder tumour response to radiation
por: McKeown, S R, et al.
Publicado: (2003) -
FISH comets show that the salvage enzyme TK1 contributes to gene-specific DNA repair
por: McAllister, Katherine A., et al.
Publicado: (2014) -
Detection of replicative integrity in small colonic biopsies using the BrdUrd comet assay
por: McGlynn, A P, et al.
Publicado: (2003) -
hTERT, MYC and TP53 deregulation in gastric preneoplastic lesions
por: Silva, Tanielly Cristina Raiol, et al.
Publicado: (2012) -
Telomerase Reverse Transcriptase (TERT) Regulation in Thyroid Cancer: A Review
por: McKelvey, Brittany A., et al.
Publicado: (2020)