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A Personalized BEST: Characterization of Latent Clinical Classes of Nonischemic Heart Failure That Predict Outcomes and Response to Bucindolol
BACKGROUND: Heart failure patients with reduced ejection fraction (HFREF) are heterogenous, and our ability to identify patients likely to respond to therapy is limited. We present a method of identifying disease subtypes using high-dimensional clinical phenotyping and latent class analysis that may...
Autores principales: | Kao, David P., Wagner, Brandie D., Robertson, Alastair D., Bristow, Michael R., Lowes, Brian D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3492337/ https://www.ncbi.nlm.nih.gov/pubmed/23144856 http://dx.doi.org/10.1371/journal.pone.0048184 |
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