A Non-Synonymous Single Nucleotide Polymorphism in an OPRM1 Splice Variant Is Associated with Fentanyl-Induced Emesis in Women Undergoing Minor Gynaecological Surgery

BACKGROUND: Fentanyl-induced emesis (FIE) is a distressing adverse effect in the postoperative setting. The genetic basis of FIE remains largely unknown, therefore, we examined whether it was associated with specific genetic variants of OPRM1, the gene encoding the main receptor target of fentanyl....

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Detalles Bibliográficos
Autores principales: Pang, Grace Su Yin, Ithnin, Farida, Wong, Yin Yee, Wang, Jing Bo, Lim, Yvonne, Sia, Alex Tiong Heng, Lee, Caroline Guat Lay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3492352/
https://www.ncbi.nlm.nih.gov/pubmed/23144877
http://dx.doi.org/10.1371/journal.pone.0048416

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