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The Limits of De Novo DNA Motif Discovery

A major challenge in molecular biology is reverse-engineering the cis-regulatory logic that plays a major role in the control of gene expression. This program includes searching through DNA sequences to identify “motifs” that serve as the binding sites for transcription factors or, more generally, a...

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Detalles Bibliográficos
Autores principales: Simcha, David, Price, Nathan D., Geman, Donald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3492406/
https://www.ncbi.nlm.nih.gov/pubmed/23144830
http://dx.doi.org/10.1371/journal.pone.0047836