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The Limits of De Novo DNA Motif Discovery
A major challenge in molecular biology is reverse-engineering the cis-regulatory logic that plays a major role in the control of gene expression. This program includes searching through DNA sequences to identify “motifs” that serve as the binding sites for transcription factors or, more generally, a...
Autores principales: | Simcha, David, Price, Nathan D., Geman, Donald |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3492406/ https://www.ncbi.nlm.nih.gov/pubmed/23144830 http://dx.doi.org/10.1371/journal.pone.0047836 |
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