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Effect of Aging and Dietary Salt and Potassium Intake on Endothelial PTEN (Phosphatase and Tensin Homolog on Chromosome 10) Function

Aging promotes endothelial dysfunction, defined as a reduction in bioavailable nitric oxide (NO) produced by the endothelial isoform of nitric oxide synthase (NOS3). This enzyme is critically regulated by phosphorylation by protein kinase B (Akt), which in turn is regulated by the lipid phosphatase,...

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Detalles Bibliográficos
Autores principales: Ying, Wei-Zhong, Aaron, Kristal J., Sanders, Paul W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3492426/
https://www.ncbi.nlm.nih.gov/pubmed/23144940
http://dx.doi.org/10.1371/journal.pone.0048715

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