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Endogenous Thrombospondin-1 Regulates Leukocyte Recruitment and Activation and Accelerates Death from Systemic Candidiasis
Disseminated Candida albicans infection results in high morbidity and mortality despite treatment with existing antifungal drugs. Recent studies suggest that modulating the host immune response can improve survival, but specific host targets for accomplishing this goal remain to be identified. The e...
Autores principales: | Martin-Manso, Gema, Navarathna, Dhammika H. M. L. P., Galli, Susana, Soto-Pantoja, David R., Kuznetsova, Svetlana A., Tsokos, Maria, Roberts, David D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3492437/ https://www.ncbi.nlm.nih.gov/pubmed/23144964 http://dx.doi.org/10.1371/journal.pone.0048775 |
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