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Endogenous Thrombospondin-1 Regulates Leukocyte Recruitment and Activation and Accelerates Death from Systemic Candidiasis

Disseminated Candida albicans infection results in high morbidity and mortality despite treatment with existing antifungal drugs. Recent studies suggest that modulating the host immune response can improve survival, but specific host targets for accomplishing this goal remain to be identified. The e...

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Detalles Bibliográficos
Autores principales: Martin-Manso, Gema, Navarathna, Dhammika H. M. L. P., Galli, Susana, Soto-Pantoja, David R., Kuznetsova, Svetlana A., Tsokos, Maria, Roberts, David D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3492437/
https://www.ncbi.nlm.nih.gov/pubmed/23144964
http://dx.doi.org/10.1371/journal.pone.0048775

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