Inhibition of Both Protease and Helicase Activities of Hepatitis C Virus NS3 by an Ethyl Acetate Extract of Marine Sponge Amphimedon sp

Combination therapy with ribavirin, interferon, and viral protease inhibitors could be expected to elicit a high level of sustained virologic response in patients infected with hepatitis C virus (HCV). However, several severe side effects of this combination therapy have been encountered in clinical...

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Detalles Bibliográficos
Autores principales: Fujimoto, Yuusuke, Salam, Kazi Abdus, Furuta, Atsushi, Matsuda, Yasuyoshi, Fujita, Osamu, Tani, Hidenori, Ikeda, Masanori, Kato, Nobuyuki, Sakamoto, Naoya, Maekawa, Shinya, Enomoto, Nobuyuki, de Voogd, Nicole J., Nakakoshi, Masamichi, Tsubuki, Masayoshi, Sekiguchi, Yuji, Tsuneda, Satoshi, Akimitsu, Nobuyoshi, Noda, Naohiro, Yamashita, Atsuya, Tanaka, Junichi, Moriishi, Kohji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3492463/
https://www.ncbi.nlm.nih.gov/pubmed/23144928
http://dx.doi.org/10.1371/journal.pone.0048685

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