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On Ribosome Load, Codon Bias and Protein Abundance
Different codons encoding the same amino acid are not used equally in protein-coding sequences. In bacteria, there is a bias towards codons with high translation rates. This bias is most pronounced in highly expressed proteins, but a recent study of synthetic GFP-coding sequences did not find a corr...
Autores principales: | Klumpp, Stefan, Dong, Jiajia, Hwa, Terence |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3492488/ https://www.ncbi.nlm.nih.gov/pubmed/23144899 http://dx.doi.org/10.1371/journal.pone.0048542 |
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