Cargando…

Association of UHRF1 with H3K9 methylation directs the maintenance of DNA methylation

A fundamental challenge in mammalian biology has been elucidating mechanisms linking DNA methylation and histone post-translational modifications. Human UHRF1 (ubiquitin-like, PHD and RING finger containing 1) has multiple domains that bind chromatin and is implicated genetically in DNA methylation...

Descripción completa

Detalles Bibliográficos
Autores principales:	Rothbart, Scott B., Krajewski, Krzysztof, Nady, Nataliya, Tempel, Wolfram, Xue, Sheng, Badeaux, Aimee I., Barsyte-Lovejoy, Dalia, Martinez, Jorge Y., Bedford, Mark T., Fuchs, Stephen M., Arrowsmith, Cheryl H., Strahl, Brian D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2012
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3492551/ https://www.ncbi.nlm.nih.gov/pubmed/23022729 http://dx.doi.org/10.1038/nsmb.2391

Ejemplares similares

Hemi-methylated DNA regulates DNA methylation inheritance through allosteric activation of H3 ubiquitylation by UHRF1
por: Harrison, Joseph S, et al.
Publicado: (2016)

Comparative biochemical analysis of UHRF proteins reveals molecular mechanisms that uncouple UHRF2 from DNA methylation maintenance
por: Vaughan, Robert M, et al.
Publicado: (2018)

The histone and non-histone methyllysine reader activities of the UHRF1 tandem Tudor domain are dispensable for the propagation of aberrant DNA methylation patterning in cancer cells
por: Vaughan, Robert M., et al.
Publicado: (2020)

The finger loop of the SRA domain in the E3 ligase UHRF1 is a regulator of ubiquitin targeting and is required for the maintenance of DNA methylation
por: Vaughan, Robert M., et al.
Publicado: (2019)

The Growing Complexity of UHRF1-Mediated Maintenance DNA Methylation
por: Xie, Si, et al.
Publicado: (2018)

Role of UHRF1 in de novo DNA methylation in oocytes and maintenance methylation in preimplantation embryos
por: Maenohara, Shoji, et al.
Publicado: (2017)

Histone peptide microarray screen of chromo and Tudor domains defines new histone lysine methylation interactions
por: Shanle, Erin K., et al.
Publicado: (2017)

Targeting human SET1/MLL family of proteins
por: Vedadi, Masoud, et al.
Publicado: (2017)

Discovery of a chemical probe for the L3MBTL3 methyl-lysine reader domain
por: James, Lindsey I., et al.
Publicado: (2013)

Structural and mechanistic insights into UHRF1-mediated DNMT1 activation in the maintenance DNA methylation
por: Li, Tao, et al.
Publicado: (2018)

Binding specificity and function of the SWI/SNF subunit SMARCA4 bromodomain interaction with acetylated histone H3K14
por: Enríquez, Paul, et al.
Publicado: (2021)

Methylated-UHRF1 and PARP1 interaction is critical for homologous recombination
por: Hahm, Ja Young, et al.
Publicado: (2020)

SET8 prevents excessive DNA methylation by methylation-mediated degradation of UHRF1 and DNMT1
por: Zhang, Huifang, et al.
Publicado: (2019)

Structure and Function of Protein Arginine Methyltransferase PRMT7
por: Halabelian, Levon, et al.
Publicado: (2021)

Teneurin C-Terminal Associated Peptide (TCAP)-1 and Latrophilin Interaction in HEK293 Cells: Evidence for Modulation of Intercellular Adhesion
por: Husić, Mia, et al.
Publicado: (2019)

Involvement of PGC7 and UHRF1 in the regulation of DNA methylation of the IG-DMR in the imprinted Dlk1-Dio3 locus : PGC7 and UHRF1 regulats IG-DMR methylation
por: Yu, Mengying, et al.
Publicado: (2022)

Methylation of UHRF1 by SET7 is essential for DNA double-strand break repair
por: Hahm, Ja Young, et al.
Publicado: (2019)

The multi-functionality of UHRF1: epigenome maintenance and preservation of genome integrity
por: Mancini, Monica, et al.
Publicado: (2021)

UHRF1 Induces Methylation of the TXNIP Promoter and Down-Regulates Gene Expression in Cervical Cancer
por: Kim, Min Jun, et al.
Publicado: (2021)

Alternative splicing and allosteric regulation modulate the chromatin binding of UHRF1
por: Tauber, Maria, et al.
Publicado: (2020)

Telomere dysfunction cooperates with epigenetic alterations to impair murine embryonic stem cell fate commitment
por: Criqui, Mélanie, et al.
Publicado: (2020)

PRMT5 regulates ATF4 transcript splicing and oxidative stress response
por: Szewczyk, Magdalena M., et al.
Publicado: (2022)

Methylation-state-specific recognition of histones by the MBT repeat protein L3MBTL2
por: Guo, Yahong, et al.
Publicado: (2009)

Hemi-methylated DNA opens a closed conformation of UHRF1 to facilitate its histone recognition
por: Fang, Jian, et al.
Publicado: (2016)

Coordinated Dialogue between UHRF1 and DNMT1 to Ensure Faithful Inheritance of Methylated DNA Patterns
por: Bronner, Christian, et al.
Publicado: (2019)

Staying true to yourself: mechanisms of DNA methylation maintenance in mammals
por: Petryk, Nataliya, et al.
Publicado: (2020)

TGF-β signaling controls Foxp3 methylation and T reg cell differentiation by modulating Uhrf1 activity
por: Sun, Xiang, et al.
Publicado: (2019)

A role for LSH in facilitating DNA methylation by DNMT1 through enhancing UHRF1 chromatin association
por: Han, Mengmeng, et al.
Publicado: (2020)

UHRF1-induced connexin26 methylation is involved in hearing damage triggered by intermittent hypoxia in neonatal rats
por: Zhang, Xingang, et al.
Publicado: (2023)

PLK1 maintains DNA methylation and cell viability by regulating phosphorylation-dependent UHRF1 protein stability
por: Peng, Yuchong, et al.
Publicado: (2023)

Dissecting the precise role of H3K9 methylation in crosstalk with DNA maintenance methylation in mammals
por: Zhao, Qian, et al.
Publicado: (2016)

Distal extracellular teneurin region (teneurin C-terminal associated peptide; TCAP) possesses independent intracellular calcium regulating actions, in vitro: A potential antagonist of corticotropin-releasing factor (CRF)
por: Hogg, David W., et al.
Publicado: (2022)

Poly-acetylated chromatin signatures are preferred epitopes for site-specific histone H4 acetyl antibodies
por: Rothbart, Scott B., et al.
Publicado: (2012)

Histone Recognition and Large-Scale Structural Analysis of the Human Bromodomain Family
por: Filippakopoulos, Panagis, et al.
Publicado: (2012)

The USP7/Dnmt1 complex stimulates the DNA methylation activity of Dnmt1 and regulates the stability of UHRF1
por: Felle, Max, et al.
Publicado: (2011)

Systematic analysis of the binding behaviour of UHRF1 towards different methyl- and carboxylcytosine modification patterns at CpG dyads
por: Schneider, Markus, et al.
Publicado: (2020)

Chromatin structure and its chemical modifications regulate the ubiquitin ligase substrate selectivity of UHRF1
por: Vaughan, Robert M., et al.
Publicado: (2018)

Direct interaction between the PRDM3 and PRDM16 tumor suppressors and the NuRD chromatin remodeling complex
por: Ivanochko, Danton, et al.
Publicado: (2019)

Comprehensive Pan-Cancer Analysis Reveals the Role of UHRF1-Mediated DNA Methylation and Immune Infiltration in Renal Cell Carcinoma
por: Pan, Xiao, et al.
Publicado: (2022)

An RNA Polymerase II-coupled function for histone H3K36 methylation in checkpoint activation and DSB repair
por: Jha, Deepak Kumar, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_nj5qug6rfl21u982cuib64ckfh