Multi-Purpose Utility of Circulating Plasma DNA Testing in Patients with Advanced Cancers

Tumor genomic instability and selective treatment pressures result in clonal disease evolution; molecular stratification for molecularly targeted drug administration requires repeated access to tumor DNA. We hypothesized that circulating plasma DNA (cpDNA) in advanced cancer patients is largely deri...

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Detalles Bibliográficos
Autores principales: Perkins, Geraldine, Yap, Timothy A., Pope, Lorna, Cassidy, Amy M., Dukes, Juliet P., Riisnaes, Ruth, Massard, Christophe, Cassier, Philippe A., Miranda, Susana, Clark, Jeremy, Denholm, Katie A., Thway, Khin, Gonzalez De Castro, David, Attard, Gerhardt, Molife, L. Rhoda, Kaye, Stan B., Banerji, Udai, de Bono, Johann S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3492590/
https://www.ncbi.nlm.nih.gov/pubmed/23144797
http://dx.doi.org/10.1371/journal.pone.0047020

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