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The response of PKD1L3 / PKD2L1 to acid stimuli is inhibited by capsaicin and its pungent analogs

Polycystic kidney disease (PKD) 2L1 protein is a member of the transient receptor potential (TRP) ion channel family. In circumvallate and foliate papillae, PKD2L1 is coexpressed with PKD1L3. PKD2L1 and PKD1L3 interact through their transmembrane domain and the resulting heteromer PKD1L3/PKD2L1 owns...

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Detalles Bibliográficos
Autores principales: Ishii, Sho, Kurokawa, Azusa, Kishi, Mikiya, Yamagami, Keigo, Okada, Shinji, Ishimaru, Yoshiro, Misaka, Takumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3492849/
https://www.ncbi.nlm.nih.gov/pubmed/22420714
http://dx.doi.org/10.1111/j.1742-4658.2012.08566.x