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Plasma Norepinephrine in Hypertensive Rats Reflects α(2)-Adrenoceptor Release Control Only When Re-Uptake is Inhibited
α(2)-adrenoceptors (AR) lower central sympathetic output and peripheral catecholamine release, thereby protecting against sympathetic hyperactivity and hypertension. Norepinephrine re-uptake–transporter effectively (NET) removes norepinephrine from the synapse. Overflow to plasma will therefore not...
Autores principales: | Berg, Torill, Walaas, Sven Ivar, Roberg, Bjørg Åse, Huynh, Trang Thi, Jensen, Jørgen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3492874/ https://www.ncbi.nlm.nih.gov/pubmed/23162530 http://dx.doi.org/10.3389/fneur.2012.00160 |
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