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Synthetic disulfide-bridged cyclic peptides mimic the anti-angiogenic actions of chondromodulin-I
Chondromodulin-I (ChM-I) is a 25-kDa glycoprotein in cartilage matrix that inhibits angiogenesis. It contains two distinctive structural domains: the N-terminal third of the molecule is a hydrophilic domain that contains O-linked and N-linked oligosaccharide chains, and the C-terminal two-thirds is...
Autores principales: | Miura, Shigenori, Kondo, Jun, Kawakami, Toru, Shukunami, Chisa, Aimoto, Saburo, Tanaka, Hideyuki, Hiraki, Yuji |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3492907/ https://www.ncbi.nlm.nih.gov/pubmed/22429838 http://dx.doi.org/10.1111/j.1349-7006.2012.02276.x |
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