Cargando…

The pig as a model for investigating the role of neutrophil serine proteases in human inflammatory lung diseases

The serine proteases released by activated polymorphonuclear neutrophils [NSPs (neutrophil serine proteases)] contribute to a variety of inflammatory lung diseases, including CF (cystic fibrosis). They are therefore key targets for the development of efficient inhibitors. Although rodent models have...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bréa, Déborah, Meurens, François, Dubois, Alice V., Gaillard, Julien, Chevaleyre, Claire, Jourdan, Marie-Lise, Winter, Nathalie, Arbeille, Brigitte, Si-Tahar, Mustapha, Gauthier, Francis, Attucci, Sylvie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Portland Press Ltd. 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3492928/ https://www.ncbi.nlm.nih.gov/pubmed/22860995 http://dx.doi.org/10.1042/BJ20120818

Ejemplares similares

The Pig: A Relevant Model for Evaluating the Neutrophil Serine Protease Activities during Acute Pseudomonas aeruginosa Lung Infection
por: Chevaleyre, Claire, et al.
Publicado: (2016)

Regulation of Neutrophil Serine Proteases by Intracellular Serpins
por: Benarafa, Charaf
Publicado: (2015)

Camostat Does Not Inhibit the Proteolytic Activity of Neutrophil Serine Proteases
por: Assylbekova, Akmaral, et al.
Publicado: (2022)

Hindrance of the Proteolytic Activity of Neutrophil-Derived Serine Proteases by Serine Protease Inhibitors as a Management of Cardiovascular Diseases and Chronic Inflammation
por: Burster, Timo, et al.
Publicado: (2021)

Processing of Neutrophil α-Defensins Does Not Rely on Serine Proteases In Vivo
por: Glenthøj, Andreas, et al.
Publicado: (2015)

Inhibitors of Serine Proteases in Regulating the Production and Function of Neutrophil Extracellular Traps
por: Majewski, Pawel, et al.
Publicado: (2016)

Neutrophil serine proteases and their endogenous inhibitors in coronary artery ectasia patients
por: Liu, Ruifeng, et al.
Publicado: (2016)

Tailor-made inflammation: how neutrophil serine proteases modulate the inflammatory response
por: Kessenbrock, Kai, et al.
Publicado: (2010)

Neutrophil serine protease 4 is required for mast cell-dependent vascular leakage
por: AhYoung, Andrew P., et al.
Publicado: (2020)

Neutrophil maturation rate determines the effects of dipeptidyl peptidase 1 inhibition on neutrophil serine protease activity
por: Gardiner, P, et al.
Publicado: (2016)

Serine Protease Autotransporters of Enterobacteriaceae (SPATEs): Biogenesis and Function
por: Dautin, Nathalie
Publicado: (2010)

Extracellular: Plasma Membrane Proteases – Serine Proteases
por: Antalis, T.M., et al.
Publicado: (2016)

The role of Serine Proteases and Serine Protease Inhibitors in the migration of Gonadotropin-Releasing Hormone neurons
por: Drapkin, Paola T, et al.
Publicado: (2002)

Absence of the neutrophil serine protease cathepsin G decreases neutrophil granulocyte infiltration but does not change the severity of acute pancreatitis
por: Aghdassi, Ali A., et al.
Publicado: (2019)

Serine Proteases of Parasitic Helminths
por: Yang, Yong, et al.
Publicado: (2015)

Design of a Selective Substrate and Activity Based Probe for Human Neutrophil Serine Protease 4
por: Kasperkiewicz, Paulina, et al.
Publicado: (2015)

Serine protease inhibitor derived from Trichinella spiralis (TsSERP) inhibits neutrophil elastase and impairs human neutrophil functions
por: Kobpornchai, Porntida, et al.
Publicado: (2022)

Computed Tomography (CT) Scanning Facilitates Early Identification of Neonatal Cystic Fibrosis Piglets
por: Guillon, Antoine, et al.
Publicado: (2015)

The neutrophil serine protease inhibitor serpinb1 preserves lung defense functions in Pseudomonas aeruginosa infection
por: Benarafa, Charaf, et al.
Publicado: (2007)

Cloning of cDNA for proteinase 3: a serine protease, antibiotic, and autoantigen from human neutrophils
Publicado: (1990)

The Serine Protease Inhibitor Elafin Maintains Normal Growth Control by Opposing the Mitogenic Effects of Neutrophil Elastase
por: Caruso, Joseph A., et al.
Publicado: (2014)

An optimized method of extracting and quantifying active Neutrophil serine proteases from human whole blood cells
por: Basso, Jessica, et al.
Publicado: (2022)

Antibodies to Serine Proteases in the Antiphospholipid Syndrome
por: Chen, Pojen P., et al.
Publicado: (2010)

Mutations in a novel serine protease PRSS56 in families with nanophthalmos
por: Orr, Andrew, et al.
Publicado: (2011)

Transmembrane serine protease 2 is a prognostic factor for lung adenocarcinoma
por: Schneider, Marc A., et al.
Publicado: (2022)

Neutrophil elastase, an acid-independent serine protease, facilitates reovirus uncoating and infection in U937 promonocyte cells
por: Golden, Joseph W, et al.
Publicado: (2005)

Schistosoma mansoni SmKI-1 serine protease inhibitor binds to elastase and impairs neutrophil function and inflammation
por: Morais, Suellen B., et al.
Publicado: (2018)

A Putative Serine Protease is Required to Initiate the RIPK3-MLKL—Mediated Necroptotic Death Pathway in Neutrophils
por: Wang, Xiaoliang, et al.
Publicado: (2021)

Internal Disulfide Bonding and Glycosylation of Interleukin-7 Protect Against Proteolytic Inactivation by Neutrophil Metalloproteinases and Serine Proteases
por: Vandooren, Jennifer, et al.
Publicado: (2021)

255 A Bacterial Serine Protease Inhibitor, Ecotin Inhibits Neutrophil Elastase in Cystic Fibrosis Airway Samples
por: Fantone, Kayla, et al.
Publicado: (2022)

Simultaneous inhibition of two neutrophil serine proteases by the S. aureus innate immune evasion protein EapH2
por: Mishra, Nitin, et al.
Publicado: (2023)

Genome-wide survey of prokaryotic serine proteases: Analysis of distribution and domain architectures of five serine protease families in prokaryotes
por: Tripathi, Lokesh P, et al.
Publicado: (2008)

Membrane-Anchored Serine Proteases in Health and Disease
por: Antalis, Toni M., et al.
Publicado: (2011)

Electrostatic recognition in substrate binding to serine proteases
por: Waldner, Birgit J., et al.
Publicado: (2018)

Structural and functional diversities in lepidopteran serine proteases
por: Srinivasan, Ajay, et al.
Publicado: (2006)

Fungal lifestyle reflected in serine protease repertoire
por: Muszewska, Anna, et al.
Publicado: (2017)

Effects of Bacillus Serine Proteases on the Bacterial Biofilms
por: Mitrofanova, Olga, et al.
Publicado: (2017)

Serine Proteases in the Lectin Pathway of the Complement System
por: Andrade, Fabiana A., et al.
Publicado: (2017)

Diarylethene‐Based Photoswitchable Inhibitors of Serine Proteases
por: Babii, Oleg, et al.
Publicado: (2021)

Role of Serine Proteases at the Tumor-Stroma Interface
por: Tagirasa, Ravichandra, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_a3ivtac9nck6rebp2c5csjjdis