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Upfront Bevacizumab and Temozolomide or Fotemustine before Radiotherapy for Patients with Glioblastoma and Severe Neurological Impairment at Diagnosis
Unresectable glioblastomas with severe neurological impairment at diagnosis have a poor prognosis. The conventional approach using a temozolomide-based chemoradiotherapy has limited efficiency on patients in the RTOG RPA V–VI classes. The activity of the antiangiogenic monoclonal antibody bevacizuma...
Autores principales: | Bihan, Celina, Foscolo, Sylvain, Boone, Mathieu, Blonski, Marie, Coutte, Alexandre, Darlix, Amélie, Beauchesne, Patrick, Lefranc, Michel, Lorgis, Veronique, Taillandier, Luc, Chauffert, Bruno |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
S. Karger AG
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3492967/ https://www.ncbi.nlm.nih.gov/pubmed/23139667 http://dx.doi.org/10.1159/000343139 |
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