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Repeated Treatment for Macular Edema in Vein Occlusion by Intravitreal Implant of Dexamethasone

BACKGROUND: Macular edema (ME) treatment has benefited from the recent intravitreal pharmacotherapy development of an intravitreal implant of dexamethasone (Ozurdex(®), Allergan, Irvine, Calif., USA). However, its efficiency has never been illustrated beyond 3 injections. CASE PRESENTATION: We repor...

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Detalles Bibliográficos
Autores principales: Matonti, Frederic, Hoffart, Louis, Baeteman, Christophe, Denis, Danièle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3492995/
https://www.ncbi.nlm.nih.gov/pubmed/23139679
http://dx.doi.org/10.1159/000343643
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author Matonti, Frederic
Hoffart, Louis
Baeteman, Christophe
Denis, Danièle
author_facet Matonti, Frederic
Hoffart, Louis
Baeteman, Christophe
Denis, Danièle
author_sort Matonti, Frederic
collection PubMed
description BACKGROUND: Macular edema (ME) treatment has benefited from the recent intravitreal pharmacotherapy development of an intravitreal implant of dexamethasone (Ozurdex(®), Allergan, Irvine, Calif., USA). However, its efficiency has never been illustrated beyond 3 injections. CASE PRESENTATION: We report the case of a 75-year-old woman with inferior branch vein occlusion, who, after laser photocoagulation treatment and recurrence after intravitreal injection of triamcinolone, benefited from 4 injections of Ozurdex. Her macular thickness and visual acuity (VA) progression were assessed for 17 months. CONCLUSIONS: This case report highlights the quick efficiency of Ozurdex on VA and ME with good reproducibility and tolerance, and without tachyphylaxis phenomenon. This is the first illustrated description of 4 consecutive injections for ME induced secondary to retinal vein occlusion.
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spelling pubmed-34929952012-11-08 Repeated Treatment for Macular Edema in Vein Occlusion by Intravitreal Implant of Dexamethasone Matonti, Frederic Hoffart, Louis Baeteman, Christophe Denis, Danièle Case Rep Ophthalmol Published online: October, 2012 BACKGROUND: Macular edema (ME) treatment has benefited from the recent intravitreal pharmacotherapy development of an intravitreal implant of dexamethasone (Ozurdex(®), Allergan, Irvine, Calif., USA). However, its efficiency has never been illustrated beyond 3 injections. CASE PRESENTATION: We report the case of a 75-year-old woman with inferior branch vein occlusion, who, after laser photocoagulation treatment and recurrence after intravitreal injection of triamcinolone, benefited from 4 injections of Ozurdex. Her macular thickness and visual acuity (VA) progression were assessed for 17 months. CONCLUSIONS: This case report highlights the quick efficiency of Ozurdex on VA and ME with good reproducibility and tolerance, and without tachyphylaxis phenomenon. This is the first illustrated description of 4 consecutive injections for ME induced secondary to retinal vein occlusion. S. Karger AG 2012-10-06 /pmc/articles/PMC3492995/ /pubmed/23139679 http://dx.doi.org/10.1159/000343643 Text en Copyright © 2012 by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-Noncommercial-No-Derivative-Works License (http://creativecommons.org/licenses/by-nc-nd/3.0/). Users may download, print and share this work on the Internet for noncommercial purposes only, provided the original work is properly cited, and a link to the original work on http://www.karger.com and the terms of this license are included in any shared versions.
spellingShingle Published online: October, 2012
Matonti, Frederic
Hoffart, Louis
Baeteman, Christophe
Denis, Danièle
Repeated Treatment for Macular Edema in Vein Occlusion by Intravitreal Implant of Dexamethasone
title Repeated Treatment for Macular Edema in Vein Occlusion by Intravitreal Implant of Dexamethasone
title_full Repeated Treatment for Macular Edema in Vein Occlusion by Intravitreal Implant of Dexamethasone
title_fullStr Repeated Treatment for Macular Edema in Vein Occlusion by Intravitreal Implant of Dexamethasone
title_full_unstemmed Repeated Treatment for Macular Edema in Vein Occlusion by Intravitreal Implant of Dexamethasone
title_short Repeated Treatment for Macular Edema in Vein Occlusion by Intravitreal Implant of Dexamethasone
title_sort repeated treatment for macular edema in vein occlusion by intravitreal implant of dexamethasone
topic Published online: October, 2012
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3492995/
https://www.ncbi.nlm.nih.gov/pubmed/23139679
http://dx.doi.org/10.1159/000343643
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