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Distinct peak at 3.8 ppm observed by 3T MR spectroscopy in meningiomas, while nearly absent in high-grade gliomas and cerebral metastases

The purpose of the present study was to evaluate distinct metabolic features of meningiomas to distinguish them from other brain lesions using proton magnetic resonance spectroscopy. The study was performed on 17 meningiomas, 24 high-grade gliomas and 9 metastases. Elevated signal intensity at 3.8 p...

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Detalles Bibliográficos
Autores principales: KOUSI, EVANTHIA, TSOUGOS, IOANNIS, FOUNTAS, KONSTANTINOS, THEODOROU, KIRIAKI, TSOLAKI, EVAGGELIA, FEZOULIDIS, IOANNIS, KAPSALAKI, EFTICHIA
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3493044/
https://www.ncbi.nlm.nih.gov/pubmed/22293950
http://dx.doi.org/10.3892/mmr.2012.773
Descripción
Sumario:The purpose of the present study was to evaluate distinct metabolic features of meningiomas to distinguish them from other brain lesions using proton magnetic resonance spectroscopy. The study was performed on 17 meningiomas, 24 high-grade gliomas and 9 metastases. Elevated signal intensity at 3.8 ppm observed in low TE spectra adequately differentiated meningioma from other brain tumors while alanine was not indicative of meningioma occurrence; the presence of lipids and lactate did not provide a strong index for meningioma malignancy.